Local hyperthermia for cancer

Local hyperthermia for cancer

Local deep hyperthermia - targeted heat against tumors

Local deep hyperthermia is an innovative method of supportive cancer therapy in which only the affected tissue or organ is heated to 40 °C to 42 °C. Healthy surrounding tissue remains largely unharmed. Healthy surrounding tissue remains largely unharmed – the organism is subjected to significantly less stress than with conventional chemotherapy or radiotherapy.

Mechanism of action of local hyperthermia

A significant therapeutic effect is the activation of the immune system:

The targeted overheating causes tumour cells to form so-called heat shock proteins (HSP) – specific surface markers that the immune system recognizes as “alarm signals”. This makes cancer cells visible and vulnerable to attack, while healthy cells remain unaffected.

Advantages of local deep hyperthermia

Local deep hyperthermia is a targeted, well-tolerated procedure which, in combination with other forms of therapy, can significantly improve the treatment outcome – particularly in the case of localized tumours and therapy-resistant cancers.

Procedure for local deep hyperthermia

The treatment usually lasts 60 to 120 minutes. The patient lies relaxed on a treatment bed at a pleasant temperature. A special applicator is used to direct modulated short waves into the affected area of the body. While the surrounding healthy tissue remains largely untouched, the energy is concentrated in the tumor region. Temperatures of up to 42 °C to 45 °C are generated there, which can specifically damage or destroy cancer cells.

As with our whole-body hyperthermia, local treatment also takes place in a calm, therapeutic atmosphere – with individual, caring support from our experienced team in our day clinic.

Successful areas of application

Local deep hyperthermia has proven to be particularly effective in the following cases

  • Peritoneal metastases (peritoneal carcinomatosis)
  • Local recurrences, e.g. in the area of the female breast
  • Brain tumors
  • Skin tumors (e.g. melanomas)
  • Bone metastases
  • Lung carcinomas
  • Tumors in the abdomen
  • Prostate carcinomas
  • Inoperable tumors


It is used for:

  • Carcinomas of various organs
  • Recurrences (relapses)
  • Metastasis formation
  • Tumors of the pancreas, gallbladder and kidneys

Therapy principle

Local hyperthermia is individually tailored and often carried out in combination with conventional medical and biological therapy methods. The aim is to improve treatment success while placing as little strain on the body as possible.

Comparison: Local deep hyperthermia vs. conventional cancer therapies

Criterion

Local deep hyperthermia

Conventional therapies (chemotherapy, radiation, surgery)

Intervention in the organism

Non-invasive, no strain on the body

Partly highly invasive, stressful

Anesthesia required

No

Yes, often during surgery

Side effects

Little to none

Frequent (e.g. tiredness, nausea, hair loss)

Pain during therapy

None

Possible (e.g. postoperative, during radiation)

Form of treatment

Outpatient

Partially stationary required

Integration into other therapies

Can be combined very well

Depending on the form of therapy

Immunological effect

Promotes immune response through heat shock proteins

No targeted immunological stimulation

Aiming accuracy

Very targeted on tumor tissue

Partly unspecific, also affects healthy tissue

Free advice on hyperthermia

Our team of experts will draw up an individual treatment plan for you and answer all your questions about hyperthermia. Take the opportunity to get to know an innovative cancer therapy.